A Meta View on the Skin: Interactions between skin and human body ecosystems

Skin–brain axis, skin–microbiome interconnections

Par Anaïs BONNEFOY

In recent years, two highly dynamic research fields have emerged, highlighting the essential role of the skin within a complex network of interactions with other physiological systems. On the one hand, work on the skin–brain axis has improved understanding of the skin’s neural mechanisms and how they can be modulated. On the other hand, research on the skin microbiome has deepened knowledge of the microbial ecosystem living on the skin surface and its role in maintaining cutaneous homeostasis.

The first part of this article describes the mechanisms linking the skin and the brain. The second part focuses on interactions between the skin and the microbiome.

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